Scientists Might Have Accidentally Found A Possible Treatment For Alopecia

Scientists Might Have Accidentally Found A Possible Treatment For Alopecia


A side effect of a drug which was initially used as an immunosuppressant might one day be used to treat baldness.

Researchers have discovered that the active compound stimulates hair follicles to grow by targeting a protein which usually puts the breaks on. They published their results in the journal Plos Biology and now hope that it can be developed into a form which could be used to treat alopecia.

According to a statement by the University of Manchester’s Dr. Nathan Hawkshaw, who co-authored the study:

“The fact this new agent, which had never even been considered in a hair loss context, promotes human hair growth is exciting because of its translational potential: it could one day make a real difference to people who suffer from hair loss”.

The drug was initially designed to treat transplant patients, suppress transplant rejection and autoimmune diseases. Officially known as Cyclosporine A (CsA), it's been commonly used since the 1980s, and does, unluckily, have many side effects. One of the least severe – but most interesting – of those is the fact that it might sometimes cause unwanted hair growth.

The researchers initially tried to figure out the molecular mechanism of the drug. Then, they carried out a full gene expression analysis of individual human hair follicles, donated by people undergoing hair transplants, that had been treated with CsA. They managed to demonstrate that the drug inhibited a particular gene, SFRP1, that has in previous studies been shown to slow down or stop the growth of tissues, most significantly including hair follicles.

If that could be developed into an effective treatment, then it could have a crucial impact on those who suffer from hair loss, which for many can lead to psychological and mental distress. Treatment is insufficient at the moment, with patients either having to take one of two drugs – minoxidil and finasteride – or go under the knife and get a hair transplant. While the latter is frequently quite successful, it is pretty invasive, while the two drugs often have mixed results.

“Clearly though, a clinical trial is required next to tell us whether this drug or similar compounds are both effective and safe in hair loss patients,” Dr. Hawkshaw points out. However, for those who suffer from hair loss, knowing that new avenues are opening to explore a potential remedy will be a relief.

Reference: IFLScience

Scientists Might Have Accidentally Found A Possible Treatment For Alopecia Scientists Might Have Accidentally Found A Possible Treatment For Alopecia Reviewed by Κατερίνα Παπ on 11:14 AM Rating: 5


  1. This news is really impressive. I'm glad that progress does not stand still and scientists are dealing with this problem in detail. As an app advertising ios marketer, I often have an active and busy schedule and I was afraid that this might affect my hair. But this news cheered me up.

  2. I am bold enough among many others to state that there is now a potent cure to this sickness but many are unaware of it. I discovered that I was infected with the virus 3 months ago, after a medical check-up. My doctor told me and I was shocked, confused and felt like my world has crumbled. I was dying slowly due to the announcement of my medical practitioner but he assured me that I could leave a normal life if I took my medications (as there was no medically known cure to Herpes). I went from churches to churches but soon found that my case needed urgent attention as I was growing lean due to fear of dying anytime soon. In a bid to look for a lasting solution to my predicament, I sought for solutions from the herbal world. I went online and searched for every powerful trado-medical practitioner that I could severe, cos I heard that the African Herbs had a cure to the Herpes syndrome. It was after a little time searching the web that I came across one Dr Itua(A powerful African Herbal Doctor), who offered to help me at a monetary fee. I had to comply as this was my final bus-stop to receiving a perfect healing. My last resolve was to take my life by myself, should this plan fail. At last it worked out well. He gave me some steps to follow and I meticulously carried out all his instructions. Last month, to be precise, I went back to the hospital to conduct another test and to my amazement, the results showed that negative,Dr Itua Can As Well Cure The Following Desease…Cancer,Hiv,Herpes, Hepatitis B,Liver Inflammatory,Diabetis,Fribroid, Dercum,fibromyalgia,Get Your Ex Back,Als,SYPHILLIS. You can free yourself of this Herpes virus by consulting this great African Herbal Doctor via this e-mail: [email protected] or call and whatsapp him on +2348149277967 He will help you and his herb medication is sure. he has the cure on all disease .You can talk to me on INSTAGRAM..tashamoore219.... 


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